Accutane Progress: Clearer Skin After Two Months of Treatment

At Reena Jogi MD in Katy and Houston, Texas, we help patients achieve lasting acne control through personalized dermatology care. A recent case highlights how isotretinoin (Accutane) can make a dramatic difference in just a few months.

Case Overview

A 36-year-old male with a long history of moderate facial acne presented for a follow-up visit after two months of Accutane therapy. His acne consisted of:

• Blackheads and whiteheads

• Pimples and inflamed papules

• Cysts and nodules

• Pigmentation and scarring

He had previously tried other treatments without long-term success.

Results So Far

After two months on isotretinoin 90 mg daily, the patient reported:

• No new breakouts over the past month

• Clearer skin overall with improvement in existing acne

• Only mild side effects of dryness, with no other concerns such as mood changes, joint pain, or fatigue

Given his progress and tolerance, his treatment dose was continued at 30 mg three times daily.

Patient Counseling and Monitoring

Because isotretinoin is a high-risk medication, careful monitoring and patient education are essential. We reviewed the following with the patient:

• Bloodwork: Monthly blood tests are required to monitor safety.

• Restrictions: Do not donate blood, do not share medication, avoid elective surgery for 6 months after treatment.

• Side Effects: Watch for dryness, nosebleeds, headaches, abdominal pain, mood changes, or vision changes.

• Skin Care Routine:

  • Use gentle, non-comedogenic cleansers (Cetaphil, CeraVe, Neutrogena Oil-Free).

  • Apply lightweight moisturizers to combat dryness.

  • Use a broad-spectrum sunscreen SPF 30+ daily to protect sensitive skin.

Treatment Expectations

We counseled the patient that acne typically improves by 60–80% after 2–3 months of consistent therapy, with continued progress over time as cumulative dosing is reached.

Isotretinoin treatment is usually continued until a total cumulative dose of 120–150 mg/kg is achieved, ensuring lasting remission.

Key Takeaways

• Accutane can dramatically improve moderate-to-severe acne within months when used under close supervision.

• Side effect monitoring and monthly bloodwork are critical for safety.

• Moisturizers and sunscreen help patients manage dryness and protect healing skin.

At Reena Jogi MD, we guide patients in Katy and Houston, Texas, through every stage of their Accutane journey—from treatment initiation to long-term skin health.