Female Pattern Hair Loss Treated with PRP, Spironolactone & Oral Minoxidil in Houston, Texas
Location: Houston & Katy, TX
Patient Profile: 35-year-old female with a 1.5-year history of progressive diffuse hair thinning
Overview
Hair loss in women is a distressing, often stigmatized issue that affects confidence and quality of life. In our dermatology practice in Houston and Katy, Texas, we frequently see women experiencing diffuse hair loss due to androgenetic alopecia (AGA)—a genetically-driven form of hair thinning. In this case, a 35-year-old female patient presented with longstanding scalp hair loss and a maternal family history of similar patterns. This case highlights a tailored, multi-modal treatment plan using Platelet-Rich Plasma (PRP) therapy, oral minoxidil, and spironolactone.
Initial Consultation and Diagnosis
The patient reported gradual onset hair thinning over the past 18 months, with no current treatment after discontinuing a previous compounded topical. Her hair loss pattern and family history (maternal grandmother and mother) pointed to androgenetic alopecia. A dermatoscopic scalp examination confirmed diffuse thinning and miniaturization typical of AGA, with no signs of scarring or inflammation.
Customized Treatment Plan
After an in-depth discussion of her options, the patient chose a combination therapy approach including:
Platelet-Rich Plasma (PRP) Injections: Stimulates natural hair regrowth using growth factors from the patient's own blood.
Oral Minoxidil (2.5 mg): A well-tolerated off-label systemic treatment known to enhance hair density and slow shedding.
Spironolactone (50 mg BID): A hormone-blocking medication used in women to reduce androgen-driven hair follicle miniaturization.
Baseline photographs were taken before initiating treatment.
Medication Counseling & Safety
Oral Minoxidil: The patient was counseled on expected initial shedding (within 8–10 weeks), with potential side effects including swelling, dizziness, and blood pressure changes. She was instructed to start with a half tablet and increase to a full dose if well tolerated.
Spironolactone: Counseling included potential side effects such as fatigue, menstrual irregularities, and elevated potassium levels. Lab monitoring was discussed, and strict pregnancy precautions were emphasized.
First PRP Session: What to Expect
The procedure began with a blood draw and sterile centrifugation. A total of 7cc of PRP was injected into the subdermal scalp, with pain control achieved via Zimmer cooling. The patient tolerated the session well. Post-procedure care included avoiding harsh products or hair dye for 2–3 days and continuing existing treatments.
Follow-Up Plan
The patient is scheduled to return in one month for her second PRP session. Progress will be tracked with updated photography and adjustments to therapy based on response and tolerability.
Takeaway for Women in Katy & Houston Facing Hair Loss
This case emphasizes the importance of personalized hair loss management using evidence-based therapies. For women experiencing patterned hair thinning in Houston and Katy, Texas, treatment options like PRP, oral minoxidil, and spironolactone offer new hope. Early intervention leads to better outcomes—schedule your consultation with Dr. Reena Jogi to explore solutions tailored to your needs.
