Case Report: Chronic Hair Loss After COVID Leading to Androgenetic Alopecia and Early CCCA

Katy & Houston, Texas Hair Loss Specialist – Reena Jogi, MD

Patient Background

A 47-year-old female presented as a new patient to our hair loss clinic with concerns of progressive scalp hair thinning that had been ongoing for approximately three years. The patient reported that her hair loss began after a COVID-19 infection, at which time she was diagnosed with telogen effluvium (TE). While some regrowth occurred, she felt that her hair density—particularly at the crown and vertex scalp—never fully recovered.

She had previously tried multiple therapies, including oral and topical minoxidil, finasteride (Propecia), ketoconazole shampoo, Nutrafol supplements, and intralesional Kenalog (ILK) injections, which helped partially but did not fully restore crown density. She discontinued minoxidil and supplements about a year prior to her visit and felt her hair growth had since stalled.

Clinical Examination

A comprehensive scalp and hair examination was performed using dermoscopy. The patient was alert, well-nourished, and in no acute distress.

Key findings included:

  • Diffuse thinning with prominence at the crown and vertex

  • Positive hair pull test

  • Findings most consistent with androgenetic alopecia (AGA)

  • Early signs of central centrifugal cicatricial alopecia (CCCA) involving the central scalp

Given the mixed clinical picture of patterned hair loss, diffuse non-scarring alopecia, and early scarring changes, a punch biopsy was recommended to further confirm the diagnosis and guide long-term management.

Diagnosis

  • Androgenetic Alopecia (L64.8) – primary cause of ongoing thinning

  • Diffuse Non-Scarring Hair Loss – likely residual from prior telogen effluvium

  • Early Central Centrifugal Cicatricial Alopecia (L66.81) – affecting the central scalp/vertex

This case highlights how post-COVID hair shedding can unmask or accelerate underlying genetic and inflammatory hair loss conditions.

Treatment Plan

After an extensive discussion of treatment options, risks, benefits, and expectations, the patient elected to proceed with a multi-modal medical hair restoration plan, including:

Medical Therapy

  • Oral Minoxidil 2.5 mg daily

  • Oral Finasteride 5 mg daily (with detailed counseling on teratogenic risks)

  • Topical Minoxidil 12% with Tretinoin 0.025% solution applied daily

  • Fluocinonide 0.05% topical solution for scalp inflammation related to early CCCA

The patient was counseled extensively on:

  • Expected initial shedding with minoxidil

  • Possible side effects of oral minoxidil, finasteride, and spironolactone

  • The slow, progressive nature of androgenetic alopecia

  • The importance of long-term consistency with therapy

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Advanced & Cosmetic Treatment Options Discussed

Because hair loss is often multifactorial, we also reviewed advanced therapies, including:

  • Platelet-Rich Plasma (PRP) therapy

  • AlmaTED™ regenerative hair restoration

  • Low-level laser therapy (LLLT)

The patient understood that these treatments are cosmetic and not covered by insurance, but may significantly improve hair density and scalp health, particularly in early CCCA.

Follow-Up & Prognosis

The patient will return in 6 months to reassess response to treatment and review biopsy results if performed. Early identification and treatment of AGA and CCCA offer the best chance for hair preservation and regrowth, especially when addressed by a board-certified dermatologist specializing in hair disorders.

Expert Hair Loss Care in Katy & Houston, Texas

At Reena Jogi, MD, we specialize in diagnosing and treating complex hair loss conditions, including post-COVID hair loss, androgenetic alopecia, CCCA, telogen effluvium, and scarring alopecias. Every patient receives a personalized, evidence-based treatment plan.

If you are experiencing hair thinning, shedding, or scalp changes, early evaluation is key.

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